Single IRB Review
What is Single IRB?
The basis for the Single IRB Model is to allow multiple institutions that are conducting the same protocol to use a single IRB for review, instead of using multiple IRBs to review the research at the sites individually. The Single IRB Model has been in use for many years, across a wide variety of studies and circumstances.
At the University of Utah, we feel that while Single IRB Review may help to streamline the study initiation process, it is important to understand all of the components of the Single IRB model that must be completed beyond just the IRB review. Efficient performance of all stages of study initiation and conduct will help to ensure multi-site research is effective and expeditious.
Your Role & Our Services
I am an Investigator using or considering the University of Utah as the SIRB for a multi-site study
I am a University of Utah Investigator using or considering an external SIRB for a multi-site study
If you would like to use an IRB other than the University of Utah IRB:
|STEP 1: Submit a Reliance Consultation request and we'll schedule a call to talk about your
|Review the HRPP Timeline to learn more about the process.
|We have a flowchart available that will walk you through the reliance process.|
I am from an SIRB that the University of Utah HRPP is relying on for a multi-site study
If you have a question, need the UU IRB to complete a local context form, or need
to speak with someone from our institution about reliance:
|The IRB Managers triage and process reliance requests at the University of Utah. You can email or call any one of them for assistance: https://irb.utah.edu/about/contact/.|
I am from an SIRB and would like the University of Utah HRPP to consider relying on us for a multi-site study
If you would like to invite the University of Utah to rely on your SIRB for a study, you should work with the study team to initiate reliance processes:
STEP 1: The PI should submit a Reliance Consultation request and we'll schedule a call to talk about your
|Reliance invitation letters can be sent to the IRB Reliance email.
|The IRB Managers review reliance requests at the University of Utah. You can contact one of them for assistance: https://irb.utah.edu/about/contact/.|